I use BizTalk on my local machine, I'm sure a lot of other people do too as it save a some time in logging on and off servers and starting up Virtual PCs etc.  The problem with desktops is that, on rare occasions, ITS hope along and renames them.  This can cause quite an issue if you happen to be using Enterprise Single Sign-On (ENTSSO) on your local machine too.

What I noticed was, after a rename, I couldn't do anything with ENTSSO in terms of use it,, start it as a service or administer it.  This is because the management tools seem do be dependent on the service itself, and the service is not started as I need to 'manage' it.

Well, today, I have had a breakthrough and wonder why on earth I didn't think of it before:

"Look in the registry."

In the registry is the following key:

HKEY_LOCAL_MACHINE\Software\Microsoft\ENTSSO\SQL

Change the name of the server value in here for your new local machine name.  Also make sure that the SQL security is OK.  If all is well, your service should start.